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INDICATION Sleep disorders: difficulty falling asleep, early and night awakenings CONTRAINDICATIONS Acute and / or severe respiratory failure, severe acute or chronic liver failure, nocturnal apnea (including presumed), due to the presence of lactose in the composition: hereditary lactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome; pregnancy; lactation period; children's age (up to 18 years); increased sensitivity to zolpidem or other component of the drug. With caution: severe myasthenia gravis, respiratory failure, mild to moderate hepatic insufficiency, depression, alcoholism, drug addiction and other addictions, Where to Buy Ambien online cash on delivery. You should not buy ambien without prescription if you have any of the contraindications listed above METHOD OF APPLICATION AND DOSAGE Inside (immediately before bed) in a single dose of 10 mg. In elderly or debilitated patients, if liver function is impaired, treatment is started with a dose of 5 mg. If necessary (insufficient clinical effect) and good tolerability of the drug, the dose may be increased to 10 mg. The maximum daily dose is 10 mg. The course of treatment should not exceed 4 weeks. With transient insomnia, the recommended course of treatment is 2-5 days, in case of a situational one - 2-3 weeks. Very short periods of treatment do not require the gradual withdrawal of the drug. In the case of long-term use of the drug to reduce the possibility of development of ricochet insomnia, the abolition of zolpidem should be carried out gradually (first a decrease in the daily dose and then the withdrawal of the drug), Best Place to Buy Ambien Cr online. Consult your physician about the individual dosage before you decide to buy ambien online. 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From the digestive system: often - diarrhea, nausea, vomiting, abdominal pain; frequency unknown - increased activity of hepatic enzymes. From the musculoskeletal system: the frequency is unknown - muscle weakness, order Zopiclone online USA. On the part of the skin: the frequency is unknown - rash, itching, urticaria, increased sweating. Allergic reactions: the frequency is unknown - angioedema. Other: often - a feeling of fatigue; infrequently it is diplopia. INTERACTIONS Alcohol enhances the sedative effect of zolpidem, joint use is not recommended. Drugs that act depressingly on the central nervous system (neuroleptics, barbiturates, other sleeping pills, anxiolytics / sedatives, antidepressants with sedative action, narcotic analgesics, antitussive central action), antiepileptic drugs, general anesthetics, antihistamines with sedative effect, antihypertensive central action; baclofen; thalidomide; pizotifen - when combined, there is an intensification of the oppressive effect on the central nervous system and the risk of respiratory depression increases; buprenorphine - risk of respiratory depression; ketoconazole (a powerful inhibitor of CYP3A4) reduces the clearance of zolpidem, in connection with which it is possible to increase its sedative effect; itraconazole (inhibitor CYP3A4) - a slight, clinically insignificant change in the pharmacokinetics and pharmacodynamics of zolpidem. Rifampicin (inducer CYP3A4) accelerates metabolism, reduces the concentration and effectiveness of zolpidem. 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